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Plants and Environment

E-ISSN: 2582-3744
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2023, Vol. 5, Issue 1

Azadirachta indica A. Juss.: Ethnobotanical knowledge, phytochemical studies, pharmacological aspects future prospects

Author(s): Ayeshabi Saeed Haji*, Siddhartha Rajendra Maurya and Nisha Shah

Affiliation: Department of Life Sciences, University of Mumbai, Vidya Nagari, Kalina, Santacruz East, Mumbai, India

Abstract: Azadirachta indica, commonly known as Neem, it is a member of the Meliaceae family, a fast-growing evergreen popular tree found commonly in India, Africa and America. All parts of the neem tree, including the seeds, fruits, twigs, leaves, flowers, roots, and bark, have traditionally been used to treat inflammation, infections, fever, skin ailments, and dental diseases. Azadirachtin, nimbolinin, nimbin, nimbidin, nimbidol, salannin, and quercetin are all useful active chemicals extracted from various plant parts. The aim of this review article provides information mainly on various pharmacological activities like Antioxidant Activity, Anti-cancer, Anti-inflammatory, Anti-bacterial, Antiviral Activity, Antifungal Activity, Antihelmethic effects, Antidiabetic action, Wound healing effect, Activity against ulcer, Orodental protection, Contraceptive, Hepatoprotective activity, Immunomodulatory and Growth Promoting, Antinephrotoxicity Effect and Antisnake venom activity of neem plant and medicinal uses. Plant extracts function as both a reducing and capping agent. Neem is a well-known medicinal plant and has been studied for the biosynthesis of nanoparticles. A. indica possesses many phytochemicals that can reduce metal ions. The nanoparticles are reported to exhibit good antimicrobial, and antioxidant and cytotoxicity effects against MCF-7 and HeLa cells in vitro.

DOI: 10.22271/2582-3744.2023.mar.1

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